Study Shows that HIV Infection Contributes to Pre-Mature Aging

A study published in Molecular Cell (Methylome-wide Analysis of Chronic HIV Infection Reveals Five-Year Increase in Biological Age and Epigenetic Targeting of HLA) reports that HIV infection led to an average advance in biological aging of 4.9 years that correlates with an increased risk of mortality of 19 percent. Samples collected in the HNRC associated CNS Antiretroviral Therapy Effects Research (CHARTER) study were analyzed for epigenetic changes.

The researchers suggest that patients knowing this information could work to diminish the risks of age related diseases (cardiovascular disease, neurocognitive impairment and liver problems) by making healthy lifestyle choices regarding exercise, diet, and drug, alcohol and tobacco use.

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