The HIV Neurobehavioral Research Center is dedicated to multi-disciplinary research and strongly encourages collaborative studies with investigators external to the Center. Training opportunities are also available.
Studies at the HNRC focus on the following major scientific questions:
- What attributes of the virus, host, and host-virus interaction determine presentation of HIV-associated neurobehavioral disorders?
- What are the mechanisms by which the host-virus factors generate neural injury and neurobehavioral impairments?
- What is the role of co-factors, including other pathogens (e.g., hepatitis C infection) as well as toxic influences such as abuse of psychoactive drugs, in initiating and potentiating HIV-associated neurocognitive impairment?
- As HIV disease becomes a chronic lifelong affliction, what are the implications of neurocognitive impairment for everyday functioning, and how can experimental measures of everyday function be translated into predictors of "real world" performance?
- How can treatments be optimized to prevent or ameliorate neuroAIDS?